2-Chloro Phenyl Acetic Acid

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2-Chloro Phenyl Acetic Acid

2-Chloro Phenyl Acetic Acid, also known as o-Chloro Phenyl Acetic Acid or 2-Chlorobenzeneacetic Acid, has the chemical formula C8H7ClO2. It belongs to the class of organic compounds known as phenylacetic acids and is a white to light yellow crystalline solid at room temperature. The compound can also be referred to as 2 chlorophenyl acetic acid, a commonly used term in organic and industrial chemistry. This compound shares structural similarity with 2 phenyl acetic acid and 2 phenylethanoic acid, with the addition of a chlorine atom at the ortho position on the benzene ring, creating a more reactive chlorophenyl structure.
The compound is sparingly soluble in water but readily dissolves in organic solvents like ethanol, methanol, and acetone. It decomposes at higher temperatures. This solubility behavior is typical of compounds featuring a chlorophenyl formula, and its functional group reactivity allows for multiple synthetic applications in pharmaceuticals and agrochemicals.

Chemical Formula and Properties:

  • Chemical Formula: C8H7ClO2
  • CAS No: 2444-36-2
  • EC No: 219-480-0
  • Melting Range: 92°C - 95°C
  • Boiling Point: 145°C
  • Purity: Minimum 99.00% (by GC)
  • Moisture: Maximum 0.50%

Packaging: The product is packaged as 50 kg net weight in HDPE woven bags with polyliner.

The phenyl acetic acid structure in 2-Chloro Phenyl Acetic Acid allows it to function as an intermediate in a wide range of chemical reactions. Its chloro phenyl substitution enhances the compound’s electrophilic character, making it suitable for complex organic transformations.

Application

Agrochemicals

2-Chloro Phenyl Acetic Acid is widely used in the agrochemical sector for the production of plant growth regulators, specifically auxins. Auxins play a vital role in plant growth and development, controlling processes such as cell elongation and differentiation. Indole-3-acetic acid (IAA) and 1-naphthaleneacetic acid (NAA) are two prominent auxins derived from 2-CPAA, used to promote root development, induce rooting in cuttings, and enhance fruit setting.
Thanks to its chlorophenyl structure, this compound enables the formation of advanced derivatives with enhanced plant-regulating efficacy. The presence of the 2 chloro phenyl acetic acid core makes it ideal for developing long-lasting auxin analogs in modern agrochemical research.

Pharmaceutical Industry

The pharmaceutical industry is one of the primary consumers of 2-Chloro Phenyl Acetic Acid. It serves as a crucial intermediate in the synthesis of various drugs, including non-steroidal anti-inflammatory drugs (NSAIDs), analgesics, and antibiotics. The chloro group on the phenyl ring allows for selective functionalization and coupling reactions, enabling the production of a diverse range of drug molecules. Additionally, 2-CPAA is utilized in the synthesis of penicillin-based antibiotics.
Due to its resemblance to phenyl acetic acid and enhanced reactivity from the chloro phenyl group, it finds use in the synthesis of drug scaffolds where the phenyl acetic acid structure is modified for improved pharmacokinetics. Its precise chlorophenyl formula enables substitution and side-chain manipulation essential in the creation of novel pharmaceutical ingredients.

Chemical Intermediates

As a versatile chemical intermediate, 2-Chloro Phenyl Acetic Acid serves as a building block in various organic synthesis routes. It participates in reactions such as esterification, amidation, and substitution reactions, leading to the production of specialty chemicals and compounds used in diverse industrial applications.
The 2 chlorophenyl acetic acid backbone is a preferred choice in intermediate chemistry because of its predictable behavior under various reaction conditions. Chemists also explore derivatives of 2 phenyl acetic acid to compare reaction profiles with their chlorinated counterparts for improved yields and selectivity.

Laboratory Research

2-CPAA is an essential reagent in laboratory research, particularly in organic chemistry. It is employed in the development of new chemical transformations and the synthesis of complex organic molecules. Its unique chemical properties and availability in high purity make it a valuable tool for scientists exploring novel chemical reactions and pharmaceutical synthesis.
In experimental chemistry, the chlorophenyl structure of 2-CPAA offers a reactive handle for advanced molecule building. It is often studied alongside 2 phenylethanoic acid and standard phenyl acetic acid derivatives to better understand reaction outcomes across varied aromatic substitutions.

2-Hydroxy Phenyl Acetic Acid

This compound finds applications in the pharmaceutical industry, where it is used as an intermediate in the synthesis of certain drugs and pharmaceuticals. It can also serve as a precursor for the preparation of other chemical compounds.

2-Chloro Phenyl Acetic Acid

Like its hydroxyl counterpart, 2-Chloro Phenyl Acetic Acid is employed as an intermediate in pharmaceutical synthesis. Additionally, it is used in the production of agrochemicals, specifically auxins, which play a crucial role in plant growth regulation and development.

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Conclusion

2-Chloro Phenyl Acetic Acid (2-CPAA) is a crucial compound with a broad range of applications in the pharmaceutical, agricultural, and chemical industries. Its ability to act as a key intermediate in drug synthesis and agrochemical production makes it a sought-after compound. With ongoing advancements in synthetic chemistry, the applications of 2-CPAA are likely to expand further, contributing to advancements in various industries and scientific research.

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Introduction and Composition of 2-Chloro Phenyl Acetic Acid

2-Chloro Phenyl Acetic Acid is an important organic chemical, which lies in the group of phenylacetic acid derivatives. Due to its usage as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals, 2-Chloro Phenyl Acetic Acid finds application in many fields. The phenylacetic acid formula for the compound C8H7ClO2 has a chlorine atom attached to the benzene ring of the 2-phenyl acetic acid structure, which enhances its reactivity as a valuable precursor for industrial applications.

This 2-chloro phenyl acetic acid is produced under controlled conditions for the chlorination of phenyl acetic acid. The parameters of the reaction are closely watched to ensure the product is obtained with high purity and yield. The leading 2-chloro phenyl acetic acid manufacturers use modern synthesis techniques in order to serve the pharmaceutical and agrochemical industries.

This compound appears to be white or off-white and crystalline and has a moderately aromatic smell. It is strongly soluble in many organic solvents, such as ethanol, acetone, or ether. 2-Chlorophenyl acetic acid has a lesser solubility in water, but stability and reactivity form an essential base for a significant number of chemical formulations.

Chemical Characteristics of 2-Chloro Phenyl Acetic Acid

2-Chloro Phenyl Acetic Acid is a compound that has specific chemical properties. This compound contains a chloro functional group within its phenyl acetic acid structure, which highly influences its reactivity and stability. The molecular weight of 2-chlorophenyl acetic acid is approximately 170.59 g/mol. It has a melting point that ranges between 95-100°C.

Another crucial characteristic of the production of chloro phenyl acetic acid is that it can be used in nucleophilic substitution and esterification reactions. The former plays an important role in the synthesis of different pharmaceutical intermediates and agrochemical compounds.

In addition, 2-chloro phenyl acetic acid manufacturers will ensure that this compound is synthesized with high levels of purity for the best results in downstream processing. The increased hydrophobicity due to the presence of a chlorine atom makes this compound a good fit for lipophilic drug preparations.

Industrially, this chemical is handled under controlled conditions to prevent degradation. It remains stable under standard storage conditions but requires protection from extreme heat and moisture to maintain its chemical integrity. At Kajay Remedies we ensure that the chemical characteristics of 2-Chloro Phenyl Acetic Acid are kept in mind and the chemicals are maintained well.

Safety Precautions and Handling of 2-Chloro Phenyl Acetic Acid

Due to its chemical composition, 2-chloro phenyl acetic acid can only be handled in specific ways and should be handled under safety precautions. Direct contact of the substance with the skin, eyes, or even through its dust and vapours may cause irritation. Protective equipment such as gloves, goggles, and lab coats should be put on when handling the substance. There must be adequate ventilation during the manufacturing and storage process of chloro phenyl acetic acid. Exposure to higher concentrations causes irritation to the respiratory system. Hence, it should be well circulated in an industrial environment to prevent exposure. 2-chloro phenyl acetic acid In case of spills, absorb with inert material such as sand or vermiculite. Collect and dispose according to the local environmental code. Furthermore, this chemical should be kept in tightly closed containers in a cool, dry place away from heat sources, oxidizing agents, and moisture. At Kajay Remedies we follow periodic safety training for employees handling chloro phenyl acetic acid production ensures that workplace safety standards are maintained.

Environmental Effects of 2-Chloro Phenyl Acetic Acid

The environmental impact of 2-chloro phenyl acetic acid depends on the methods of disposal and production processes. Although it is not highly hazardous, improper disposal can contribute to soil and water contamination. Manufacturers should include waste treatment processes for 2-chloro phenyl acetic acid so that less chemical is released into the environment. Waste effluent containing residual 2-phenyl acetic acid or its derivatives should be treated by neutralization techniques or incineration to prevent ecological damage. This compound is hydrophobic in nature, and when it is released into aquatic environments, it can influence microbial populations. The regulatory bodies enforce strict environmental guidelines to ensure that the manufacturers of chloro phenyl acetic acid adopt eco-friendly practices. Sustainable synthesis routes, such as green chemistry synthesis routes, are being studied for reducing the carbon footprint of the compound 2-chlorophenyl acetic acid. Advanced waste management and recycling techniques can help industries reduce the negative effects of this compound on the environment.

Industrial Uses and Advantages of 2-Chloro Phenyl Acetic Acid

2-Chloro Phenyl Acetic Acid finds vast industrial importance, especially in pharmaceutical intermediate and agrochemicals. This compound is of major importance as a key intermediate for the synthesis of anti-inflammatory drugs, antihistamines, and muscle relaxants. The 2-chloro phenyl acetic acid suppliers deliver this compound to agrochemical plants for the formulation of herbicides and pesticides. Its chemical property endows plant growth regulators and pesticide control agents with improved effectiveness. The process of chloro phenyl acetic acid ensures high-quality standards to meet the stringent regulatory requirements in pharmaceutical and agricultural sectors. The benefits of using this compound include its high reactivity, stability, and compatibility with a wide range of chemical reactions. As research is continuously being carried out, the applications of 2-chlorophenyl acetic acid are constantly evolving, which creates new applications in material science and specialty chemical synthesis. For a trusted partner contact us at Kajay Remedies for more details.

FAQs

2-Chloro Phenyl Acetic Acid is used widely in the pharmaceutical, agrochemical, and specialty chemical industries. In the pharmaceutical industry, it is used as an intermediate in the manufacture of anti-inflammatory drugs, muscle relaxants, and antihistamines. Agrochemical industries use it in herbicide formulations and plant growth regulators to enhance agricultural productivity. Specialty chemical industries utilize its unique properties in the synthesis of fragrances and advanced materials. Major manufacturers of 2-chloro phenyl acetic acid fulfill these varied sectors with quality productions.

The importance of 2-chloro phenyl acetic acid is in its versatile chemical reactivity and as a key intermediate in multiple industrial processes. The presence of a chlorine group enhances its applicability in organic synthesis, pharmaceutical formulations, and agrochemical production. This compound facilitates cost-effective and efficient manufacturing processes, making it indispensable for industries requiring high-purity chemical intermediates.

Indeed, 2-chloro phenyl acetic acid increases process efficiency because it is highly reactive and stable in industrial applications. A building block for synthesizing complex chemical compounds, the 2-chloro phenyl acetic acid reduces reaction times and overall yields. The producers of chloro phenyl acetic acid focus on perfecting production techniques to ensure constant quality and performance, making for cost-effective industrial processes.

Pureness and stability are direct factors influencing the quality of the final product for 2-chloro phenyl acetic acid. Pharmaceutical applications are based on a high level of purity to assure drug formulations without unwanted side effects. Agrochemicals involve a contribution of this compound toward herbicides and pesticides potency and effectiveness. In fact, quality control measures implemented by manufacturers in producing 2-chloro phenyl acetic acid assure the best possible performance in its final applications.