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4-Nitrophenol

4-Nitrophenol, also commonly referred to as para nitrophenol or p nitrophenol, is an important aromatic chemical compound used in various industries. The nitrophenol structure consists of a benzene ring with two significant substituents: a hydroxyl group (-OH) and a nitro group (-NO₂). These groups are positioned opposite each other on the ring, forming what is known as the para configuration, which results in the p nitrophenol structure or 4 nitrophenol structure.
This compound appears as a crystalline solid with a distinctive para nitrophenol colour—yellow, which makes it easily recognizable. It is slightly soluble in water and demonstrates acidic properties due to the hydroxyl group. What is nitrophenol? It is an organic compound widely used as an intermediate in the manufacture of pharmaceuticals, dyes, and agrochemicals.

    Key details include:

  • Chemical Formula : C6H5NO3(p nitrophenol formula)
  • CAS No : 100-02-7
  • EC No : 202-811-7
  • Purity by Chemical Assay : Minimum 99.50%
  • Purity by Gas Chromatograph : Minimum 99.50%
  • Single Max Impurity : Maximum 0.10% by GC
  • Moisture Content % (By Karl Fischer) : Maximum 0.50%
  • Iron Content : Maximum 10 PPM
  • Packaging : The product is supplied in HDPE woven bags, each containing 50 kg net weight with a protective LDPE liner inside.

Application

One of the most prominent uses of 4 nitrophenol is as an analytical reagent. It is widely utilized in colorimetric and spectrophotometric methods because of its strong absorbance in UV and visible light regions. The characteristic para nitrophenol colour changes depending on pH, making it highly valuable as an indicator in chemical analysis. It also serves as a calibration standard in laboratories for various enzymatic assays.
In environmental analysis, p nitrophenol is often measured as a pollutant marker due to its use in the production of pesticides and other industrial chemicals. Monitoring p nitrophenol structure degradation provides key insights into environmental contamination control.

Para nitrophenol serves as a critical intermediate in organic synthesis. Its unique chemical configuration allows easy substitution and reduction reactions, making it a preferred starting material for a wide range of derivatives. For instance, the reduction of p nitrophenol structure produces important compounds like 4-aminophenol, which is widely used in pharmaceuticals.
The versatility of 4 nitrophenol comes from its reactive groups—the hydroxyl and nitro functionalities—which enable the synthesis of dyes, pigments, insecticides, herbicides, and fungicides. This adaptability makes para nitrophenol a key material for industrial applications across sectors.

In biotechnology, 4 nitrophenol acts as a model compound for studying enzymatic reactions. Its transformation into metabolites during biodegradation has made it a preferred substrate in enzyme kinetics research. Understanding the breakdown pathways of nitrophenol structure helps researchers design efficient bioremediation techniques for contaminated environments.
Additionally, derivatives of p nitrophenol are tested for potential use in medical and agricultural biotechnology, further proving its versatility beyond traditional chemical applications.

The pharmaceutical industry heavily relies on para nitrophenol as an essential intermediate for drug synthesis. It is involved in the production of analgesics, antipyretics, and other medicinal agents. 4 nitrophenol is also a precursor for manufacturing 4-nitrophenyl chloroformate, a compound crucial in peptide synthesis and drug development processes.
Apart from pharmaceuticals, para nitrophenol finds application in agrochemicals and specialty chemicals. It is used to produce fungicides, insecticides, and even in leather processing for darkening purposes.

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Packaging

The product is carefully packed in high-quality HDPE woven bags with a net weight of 50 kg and an LDPE liner inside to maintain purity and prevent contamination.

For international markets, the product is available in UN-approved HDPE drums or bags with a net weight of 25 kg, ensuring compliance with global safety and transport standards.

Conclusion

In conclusion, 4 nitrophenol (para nitrophenol) is an indispensable chemical intermediate with wide applications in pharmaceuticals, chemical synthesis, analytical chemistry, and biotechnology. Its distinct 4 nitrophenol structure and functional properties make it an ideal choice for industrial use. With its characteristic para nitrophenol colour and reliable chemical stability, this compound remains a critical component in numerous sectors.

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