
Sodium 2-Nitrophenolate
- Chemical Formula : C6H4NO3Na
- CAS No : 824-39-5
- EC No : 212-527-5
- Purity by Bromination : Minimum 76% as Na-ONP (Anhydrous)
- Purity by Gas Chromatograph : Minimum 99.50%
- Moisture content : Maximum 24.0% including water of crystallisation
- Packaging : The product is packed as 50 kg net weight in HDPE woven bags with polyliner.
About the product
Sodium 2-nitrophenolate also known as Sodium salt of 2-Nitrophenol or Sodium salt of Ortho Nitro Phenol or NaONP in short, is derived from 2-nitrophenol, a compound belonging to the phenol family. It is the Sodium Salt of 2-nitrophenol due to the Sodium (Na+) ion attached to 2-Nitrophenol molecule. The chemical formula of sodium 2-nitrophenolate is C6H4NO3Na. This compound exhibits properties derived from both 2-nitrophenol and the sodium ion. It appears as a bright red coloured solid and is highly soluble in water. Sodium 2-nitrophenolate possesses both the phenolic and ionic characteristics, combining the reactivity of the phenolate group (-O^-) with the stabilizing effects of the sodium ion.


Synthesis Methods
Sodium 2-nitrophenolate can be synthesized through various methods. One common approach involves the reaction between 2-nitrophenol and sodium hydroxide (NaOH) in an aqueous medium. This reaction results in the displacement of the hydrogen atom from the hydroxyl group by the sodium ion, forming Sodium 2-nitrophenolate. It can also be produced by reaction 2-Nitro Chloro Benzene (also known as Ortho Nitro Chloro Benzene or ONCB in short) with Sodium Hydroxide. The reaction is typically carried out at elevated temperatures and monitored to achieve optimal yields.
Application
Organic Synthesis
Sodium 2-nitrophenolate serves as a valuable building block in organic synthesis. It is used in the production of various organic compounds, such as pharmaceuticals, dyes, and agrochemicals. The phenolate group in sodium 2-nitrophenolate can undergo substitution reactions with electrophiles, enabling the introduction of different functional groups. This compound is particularly useful in the synthesis of nitro-substituted aromatic compounds, which find applications in the development of pharmaceutical drugs and agrochemicals.
Agricultural Sector
Sodium 2-nitrophenolate has proven to be an effective plant growth regulator and elicitor. When applied to crops, it stimulates growth, enhances plant defence mechanisms, and improves yield. This compound acts as a signalling molecule, activating various physiological processes in plants, including seed germination, root development, and flowering. Additionally, sodium 2-nitrophenolate exhibits antimicrobial properties, making it useful in controlling plant pathogens and improving crop health.
Pharmaceutical Industry
Sodium 2-nitrophenolate and its derivatives have demonstrated promising biological activities. They exhibit antimicrobial, antifungal, and anticancer properties. These compounds have been investigated for their potential as therapeutic agents against microbial infections and as anticancer drugs targeting specific cellular pathways. The unique chemical properties of sodium 2-nitrophenolate make it an attractive scaffold for the development of new pharmaceutical compounds.
Dye Industry
Sodium 2-nitrophenolate serves as an important intermediate in the synthesis of dyes and pigments. Its reactivity allows for the introduction of additional functional groups, enabling the production of a wide range of vibrant and stable colorants used in textiles, inks, and coatings.


Packaging
Domestic Packaging
The product is packed in HDPE woven bags with Net Weight of 50 kg and LDPE Liner inside for added protection. Also available in Fibre Drums with Net Weight of 25 kgs (Charges Extra)
Export Packaging Packaging
The product can be packed in UN Approved bags / UN Approved HDPE Drums with Net Weight of 25 kg additional LDPE Liner inside for added protection.
Differences between Sodium 2-Nitrophenolate and Sodium 4-Nitrophenolate
Sodium 2-nitrophenolate and sodium 4-nitrophenolate are two closely related compounds that differ in the position of the nitro group (-NO2) on the phenol ring. The key differences between sodium 2-nitrophenolate and sodium 4-nitrophenolateare as follows
Position of the Nitro Group
The primary difference between these compounds lies in the position of the nitro group on the phenol ring. In sodium 2-nitrophenolate, the nitro group is attached to the ortho position relative to the hydroxyl group (-OH), whereas in sodium 4-nitrophenolate, it is attached to the para position.
Chemical Structure
The difference in the position of the nitro group results in distinct chemical structures and spatial arrangements of the atoms in these compounds.
Reactivity and Applications
Due to the difference in the position of the nitro group, sodium 2-nitrophenolate and sodium 4-nitrophenolate may exhibit variations in their reactivity and applications.
Sodium 2-nitrophenolate: It serves as a valuable building block in organic synthesis, particularly in the production of pharmaceuticals, dyes, and agrochemicals. The ortho position of the nitro group allows for various substitution reactions, enabling the introduction of different functional groups. This compound is particularly useful in the synthesis of nitro-substituted aromatic compounds.
Sodium 4-nitrophenolate: It also finds applications in organic synthesis, particularly in the production of dyes and pigments. The para position of the nitro group may influence the reactivity and the types of functional groups that can be introduced into the molecule. Sodium 4-nitrophenolate is commonly used as an intermediate in the synthesis of dyes and colorants for textiles, inks, and coatings.
Sodium 2-nitrophenolate, derived from 2-nitrophenol, demonstrates remarkable versatility and holds immense potential in various industries. Its significance in organic synthesis, agriculture, pharmaceuticals, and dyes highlights its diverse range of applications. As researchers continue to explore its chemical properties and develop new synthetic methodologies, sodium 2-nitrophenolate's importance is likely to grow even further. By harnessing its potential, we can unlock new opportunities for innovation and advancement in multiple sectors, ultimately contributing to the development of sustainable solutions and improved quality of life.
