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What is 8 - Hydroxyquinoline?

8-Hydroxyquinoline commonly referred to as 8HQ, is an organic chemical compound belonging to the quinoline group. It is appreciated for its chelating ability, which implies the ability to form coherent structures with metal ions. And because of its characteristic of being able to bind with metals, 8HQ is exceptionally versatile in its uses and helps to provide stability while at the same time increasing the effectiveness of the products in which it is incorporated.

Chemical Properties

8-Hydroxyquinoline is described as a chelating agent where it can easily be complex with metal ions and these include iron, copper, and aluminum ions. These chelates are stable and thus 8HQ is ideal in the use or formulating systems that depend on the removal or stabilization of metal ions.

  • Chemical Formula : C9H7NO
  • CAS No : H8 - 24 - 3
  • Moisture : Maximum 0.5%
  • Chemical Assay : Minimum 98%
  • Purity : Minimum 99%
  • Appearance : Off-white to beige-brown color
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Application

Enhancing Hair Dye Formulations: 8-Hydroxyquinoling or 8HQ in the short form is progressively advancing itself as an important hair dye. This compound, which has an extraordinary ability to bind cations, is essential in contributions of great chelating assistances to the stabilization of hair dye products.

Dye Stability and Longevity: Piperscrone and Gans also postulate that, in hair dye formulations, 8-Hydroxyquinoline has the advantage of being able to chelate with metal ions. Some common culprits that lead to these reactions include metal ions that may originate from the water used with these hair products or are derived from other hair products that may be applied simultaneously. As a chelating agent, 8HQ ensures that the preparation of these hair colors does not lead to the said reactions, thus producing very bright and long-lasting hair colorants. To add this, it will help the hair dye to last longer, and this will enable the consumers to use it for a more extended period than they would use other hair dyes in the market.

Antimicrobial Properties: One more significant effect arising from the use of 8-Hydroxyquinoline is that the compound is naturally used in hair dye products, given its antibacterial properties. Microbial contamination of hair dyes is a real possibility due to the preparation, storage, and usage techniques employed in the application process. 8HQ acts as a biocide and retards bacterial and fungal regrowth and thus, additional compounds are not able to contaminate the hair dye making it safe to use. This preserves the product's convenience and ensures it enjoys an extended shelf life in the marketplace.

8-hydroxyquinoline is synthesized through a reaction between ortho-nitrophenol, ortho-aminophenol and acrolein. Further, Halquinol is formed by chlorination of 8-hydroxyquinoline.

Halquinol is a microbiocidal chlorinated quinoline derivative with a certain degree of antimicrobial and antifungal properties. This makes it an essential part that is used in different fields particularly those where microbial control is vital.

Applications in Veterinary Medicine Animal Health: Halquinol is widely involved in the preparations for the prevention and treatment of various bacterial and fungal infections in animals. It plays a significant role in enhancing the health status of the animals with improved growth and production.

Animal Husbandry: Halquinol is a synthetic antimicrobial agent used in the prevention and control of intestinal infections, primarily in animal husbandry. The primary application is in poultry and swine production.

This product is potent against bacteria such as E. coli and Salmonella, common agents of diarrhea and growth depression in livestock. Adding halquinol to animal feeds can help reduce the level of this kind of infection, improving health and productivity.

8-Hydroxyquinoline is frequently used in the pharma industry and biopharma segment. Its key applications include:

Topical Antiseptics and Disinfectants: It is included in preparations for antiseptic and disinfecting treatment, that is, for the prevention of infections and maintenance of sanitary conditions.

Chelating Agent for Metal Poisoning: due to its chelating properties, it also comes in handy whenever specialized medical treatment is being sought for treating a condition that arises out of poisoning by certain metals as it is capable of bonding with these metal ions and even helps in their expulsion from the body.

Antifungal and Antibacterial Agents: 8-Hydroxyquinoline active substance is used in preparations that cure many infections affecting skin and nails including fungal and bacterial infections etc. For this reason, it is a useful component of such treatments given the versatility exhibited by the polyelectrolyte in its way of eliminating pathogens.

Preservative in Pharmaceutical Formulations: Second, it is useful for the preservation of product shelf-life and integrity specifically of pharmaceutical products in that it hinders microbial invasion.

Ophthalmic Solutions: It is applied in eye drops and ointment for treating eye infections because of its effectiveness as an antimicrobial.

Dental Products: It is also used in some dental products to curb infection and facilitate oral cleanliness

In horticulture helps as a potent fungicide as well as assists in transferring micronutrients to plants, giving them better growth rate and produce quality. This places 8-Hydroxyquinoline as one of the most essential agrochemicals in today's world farming.

Analytical Chemistry: It is crucial in qualitative and quantitative analysis; it is highly useful in environmental monitoring, assessment of water quality, and identification of metal ions.

Soil Treatments: Subsequently, 8-Hydroxyquinoline is used for directly spraying on the soil to increase nutrients for plants and free from soil-borne fungal diseases. This method helps to make sure that crops require nutrients as well as defense mechanisms from the root base.

Foliar Sprays: As foliar nutrition, 8HQ has a tonic and protective action on leaves and stems where it counteracts aerial fungal diseases and makes nutrients immediately available at the site of need.

Seed Treatments: The Spraying of seeds with the compound 8-Hydroxyquinoline before planting can enable young plants to avoid the danger of becoming infested with fungi during the early stages of plant growth. This leads to improvement in the vulnerability of seedlings and intensive growth of plant life.

Packaging

The product is packed in HDPE woven bags with a Net Weight of 25 kg and has a 3-layered inner bag (Polyethylene + Aluminium Foil + Polyester Liner)and is sealed with Nitrogen purging and an additional LDPE Liner inside the 3 Layered Inner Bag for added protection.

The product can be packed in Gusseted UN Approved bags / UN Approved HDPE Drums with a Net Weight of 25 kg and having a 3-layered inner bag (Polyethylene + Aluminium Foil + Polyester Liner)and sealed with Nitrogen purging (only in bags) and an additional LDPE Liner inside the 3 Layered Inner Bag for added protection.

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Conclusion

8-hydroxyquinoline is an advanced and effective reagent that is marking its presence in several fields. Hair dye market where helps to stabilize the dyes, prevent microbial growth on hair, and offer a conditioning effect to hair for improved color. It is a powerful fungicide within agriculture and an efficient, naturally occurring chelating agent that brings necessary micronutrients to plants and discourages irresponsible farming. Additionally, its uses in the pharmaceutical companies present it as a chelating agent and antiseptic / disinfectant to enhance the efficiency and security of medications.

Kajay is proud of being the first commercial manufacturer of 8HQ in India, manufacturing everything from the raw material to the final product all by ourselves.

Kajay Remedies enjoys a prestige position as the only commercial manufacturer of 8-hydroxyquinoline within India. This chemical intermediate is truly versatile in industries like pharmaceuticals, agrochemicals, dyes, and pigments. Backed by rich experience in the domain of chemical synthesis, Kajay Remedies comes out with high-purity 8-hydroxyquinoline to satisfy the rigid quality parameters of international markets. This compound occupies a place center-stage even in chemical formulations as varied as hair dyes and animal nutrition supplements. Kajay Remedies believes in the power of research and development for improving processes to ensure leadership in both domestic and international markets.

Ortho amino phenol and ortho nitrophenol are two prominent precursors in the chemical synthesis of 8-hydroxyquinoline. This compound may undergo a series of tough reduction, diazotization, and cyclization reactions to form the final product. Due to their wide applications, such chemical intermediate reagents work in various fields within the chemical industry, from dyes and pigments to pharmaceuticals and agrochemicals.

Halquinol is an important animal nutritional compound extracted from 8-hydroxyquinoline. It acts as a growth promoter, enhances the absorption of nutrients, and controls infections of the intestines. This 8-hydroxyquinoline derivative plays a role in the maintenance of gut health and overall well-being. It forms an important part of the feeding protocols related to the animal system toward meeting the sustainable goal of the livestock industry in terms of healthier and productive animal production.

8-Hydroxyquinoline is a breakthrough in the world of hair coloring. It also plays a major role as the main chemical intermediate in high-performance hair dyes while being formulated. With its impact on the color intensity and color life, not to mention the general health of the hair, this compound has really overhauled hair coloring formulations. Being a derivative of the 2-aminophenol compound, its place inside dyeing chemicals has been noted as one of the most significant developments ever made against the beauty sector.

Kajay Remedies proudly stands as India's exclusive global exporter of 8-hydroxyquinoline. With a strong foothold in the chemical industry, we specialize in producing high-quality chemical intermediates. Our expertise in chemical synthesis ensures the production of superior 8-hydroxyquinoline, a versatile compound with applications spanning from dyes and pigments to pharmaceuticals and agriculture. Kajay Remedies' commitment to quality and customer satisfaction has solidified their position in the global market.

FAQ's

8-hydroxyquinoline represents an organic compound whose structure provides real possibility for such a variety of applications. Its derivatives are not found only in pharmaceuticals and agrochemicals but also in dyes, thus underpinning its relevance for modern chemical processes.

For 8-hydroxyquinoline choosing Kajay Remedies, unquestionably means quality, reliability, and experience. With Kajay Remedies being the lone commercial manufacturer in India, be assured of the product's purity and consistency—unmatched.

Absolutely! Kajay Remedies understands that one has to test any product before its bulk purchase. The company supplies samples up to 50 grams for free to customers for testing purposes. Just call Kajay Remedies and ask for samples, inquiring about the involved processes in acquiring them.

8-Hydroxyquinoline, mostly applied as halquinol, improves animal nutrition through increased absorption of nutrients, fighting pathogenic microorganisms, and producing general improvement in gut health.

8-hydroxyquinoline plays an important role in the chemical synthesis of dyes which creates a bright and protracted color of the hair dyes.

We will help you consult with the optimum incorporation of 8-hydroxyquinoline into your specific product or chemical formulation by Kajay Remedies' experts in chemicals.

Ortho-aminophenol and ortho-nitrophenol are the very significant precursors in the synthesis of 8-hydroxyquinoline.

Ortho-nitrophenol: is mainly acted as the oxidizing reagent for the process. It gets reduced to ortho-aminophenol, which becomes the immediate precursor to 8-hydroxy-quinoline. Ortho-aminophenol: It is the key reactant in the formation of 8-hydroxyquinoline. It follows a series of reactions, comprising cyclization, by which the final product is formed.

High-purity ortho-aminophenol and ortho-nitrophenol are required for efficient production of the product 8-hydroxyquinoline. The usage of poor-quality raw materials brings the yield and purity down; hence, for acquiring a good quality end product, the most desirable class of reactants should normally be used.